where are you? I think I read in a previous post you had her at PVSEC? I am in Mars and my friends have a lab (he's 9) who is having some of the same troubles as your girl. Did hers come on suddenly? Their dog was seemingly fine one day then by bedtime he was in too much pain to stand up, barely. Their vet can not discover a cause either and they are afraid they are going to have to put him down. I don't know if he screams but he is in severe pain and won't eat bc of it. He hardly moves and can't walk to do his business. They've had him on some drugs (antibiotics, pain meds, not sure what else) but they are fairly poor and can't afford to do a lot more. Their vet first suspected Lyme, and most recently said he has a damaged but not torn ACL. Still, he is way worse off than 'just' that. I hope there is not some strange new disease cropping up here in eastern PA! Prayers for Sable, I hope she gets well again.