We lived in the same house until Cookie was 11. She didn't deal well with the move initially. One day, she tried to "go home." My brother lost track of her for just a minute or two, and she was gone. By the time he got to the end of the 1/4 mile driveway, Cookie was actually ON the 4-lane highway, heading for the old house. My brother ran out into traffic to save her. It's a miracle they weren't both killed. She eventually did settle in well, but she is never, EVER allowed off-leash outside the fenced backyard. It's a shame, because we have 32 beautiful acres of prairie and woods.
After Cookie was diagnosed with cancer last November, she has lived periodically with me in the town where I attend school. She has some separation anxiety, but generally has handled the change well. She knows that we get to go home sometimes on the weekends, so it's kind of like a vacation--she gets to be an only dog for a while!