My 6 month old Rocky has acne on his chin and has had it off and on since i've got him. It did get quite bad though and so we are currently doing a 3 week set of antibiotics called Novo Lexin twice daily and washing his face every 24hrs with Pyoben Shampoo that we have to leave on for 5 minutes and then wash off. If this doesn't work we may have to do another round of the meds but his face already looks much better. If they don't clear up and start to bother your puppy, you might want to consider taking her into the vet.