we haven't had any problems with pooping/peeing, just mega drooling and barking, whining, etc. in the crate...i would bet this would help with your problems too, if he's doing that out of anxiety, this med will help him calm down enough so he doesn't feel the need to mess the house. we started Riley on it when he was 5 months...and his own major growth has already helped our weaning as we haven't ever increased the dosage...one bonus. we also went through a behaviorist prior to the meds, which didn't work for us, i think it was just way too spiraled out of control. but i would suggest seeking out alternatives such as a behaviorist before doing the meds, but don't rule them out...their use in conjunction with behavioral modification is the best way to go i believe.