Ummmmm.....never.
Rabies is required by law so of course I can't legally advise against that (actually, since I'm not a vet, maybe I can, I'll have to find out).
Of course, this assumes that you are also providing them the opportunity for vibrant good health - a natural raw food diet, fresh clean (non-chemical-laden) water, fresh air and sunlight, ample exercise, no toxins, mental stimulation, love. They are all part of the whole picture, none less important than the other.
I know many breeders who have not vaccinated their dogs - for anything - for decades, and have not had the diseases that others vaccinate for (and sometimes still get!).
If you feel you must vaccinate, there are some protocols that are less dangerous than the standard bombardment practiced by most vets today. (Did you know, when you consider that puppy shots are combos of 5 to 7 vaccinations in one shot, the 'typical' puppy has received an average of 24 vaccinations by the time they are 4 months old? Scary.) The one I'm most inclined to follow if I vaccinate puppies is Dr. Martin Goldstein's, which is one distemper vaccination at 11 weeks (never before) and then a couple of weeks later, parvo. (These are distemper *only* and parvo *only*, not the combo-cocktails most vets give.) Then rabies as required by law. That's it, ever. And actually, I would probably give the first shot at 14-16 weeks, based on reasearch from the University of Wisconsin:
http://www.ivis.org/advances/Infect...er_frm.asp?LA=1
Dr. Jean Dodds, who has done a lot of reasearch on autoimmune disease, has a vaccination protocol here:
http://www.ighawaii.com/naturally/doddsvac.html
Even if you feel you must vaccinate as often as the vets say to, please at least follow the Colorado State Vaccination Protocol (UCDavis has the same protocol)
http://www.cvmbs.colostate.edu/vth/savp2.html
Yearly boosters are not recommended and not needed. Even the vet schools are coming around to this. Kirk's Current Veterinary Therapy (an "essential" reference book for vets) speaks out against yearly boosters. The only reason for a vet to insist on them is money.
Here are some previous threads:
http://www.boxerworld.com/forums/showthread.php?s=&threadid=6296
http://www.boxerworld.com/forums/showthread.php?s=&threadid=3336