Boxer histiocytic ulcerative colitis/proctitis

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dmjjweaver

Boxer Pal
Socrates, our approximately 1 yr old brindle boxer that we have had for a litle more than 6 months, was rescued from a poor home situation. He appears happy, energetic, but skinny. He has had a chronic problem with what I assume is colitis/protitis, passing bloody runny stools, straining and does not gain weight. Our local vet has recommended a high protein diet w/ an allergy free dog food, which has not brought a change in his condition. During research I found this condition is found in young Boxers (< 2 yrs old) called chronic histiocytic ulcertive colitis/proctitis, which is idiopathic (don't know why it happens) ulcertive form. I read an article recommending a TBspn of yogurt, which I will try. I am intrested in hearing about treatment options (sulfasalazine/steroids)that others may have tried, what are the prognosis, cure rates or remissions, and any other suggestions. I read an article that recommends these animals be destroyed, which I would rather not consider. We are looking for a new vet, which may be more helpful in treatment options. Any help would be greatly appreciated. Thank you. dmjjweaver@aol.com














Dennis and Mary
dmjjweaver@aol.com
 

Sasha's Mom

Boxer Booster
Colitis

Sasha was diagnosed with colitis about two months ago. From what I understand there is a broad range between basic colitis, which I believe can be controlled with diet, and chronic histiocytic ulcerative colitis. BTW, I've never read anything suggesting they be destroyed due to this! There have been previous threads on this topic and I found the information extremely helpful (if you perform a search for "colitis" and/or "IBD" you should find them).

After ruling out whipworms or another type of parasite, Sasha was placed on sulfasalazine and a very strict hypo-allergenic diet (Walthams Selected Proteins) and her symptoms are improving. She still sometimes has blood tinged stool, but they are firm and no longer runny. Her symptoms never seemed to bother her either, but one thing I have noticed is that her appetite has increased significantly since we started this course of treatment. She's always been on the petite side (hovering around 50 lbs.) and is now 55 lbs. and looks great (may have to start extending our walks to avoid love handles)! We are also going to start adding the yogurt to her diet (this was suggested by a few other Boxerworld members) :) . Hopefully, we will be able to wean her off the medication and just continue with the hypo-allergenic food. It's a bit pricey, but not prohibitively so (and I'd pay twice what I'm paying to make sure it doesn't re-occur).

Good luck and keep us posted on Socrates! Sasha has a follow-up this weekend - I'll let you know if anything changes.

Susan
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I agree...there are a few other posts on this topic. Amaya was diagnosed with colitis last summer as a puppy. She had mucous in the stools and blood.

We the diarreha first started we put her on Hill Prescription Diet I/D which is made to be gentle on the intestines and is high in fiber (Ask your vet about it). We tried to treat with diarehha medication which did not work. We also ruled out worms.

Eventually she was placed on metronidazole (flagyl) which helped a lot. We were able to slowly wean her off the medication about 2 months later. She has been on I/D for the last 6 months mainly because we didnt want to mess with anything. I am trying to change her to Hill Senstive Stomache in the next few weeks.

We carefully watch treats and rawhides rarely. We also give missing link supplement which is high in fiber and digestive enzymes. Amaya has been problem free for at least 6 months now.

Good luck.
 

susan fulcher

Super Boxer
I found a boxer 1 1\2 years ago and she had parvo,along with the parvo she had diarreah with blood.I used aholistic vet and we used no antibiotics.She also let the diarreah run its course,that took afew months of diarreah and blood.But one week it just stopped.She also had a problem putting weight on and my vet said some young dogs take time to put weight on especially after such an illness.She went from 30lbs to a a 48 lbs. boxer but it took awhile.She also was put on a barf diet from the start.You have a holistic vet in texas who is good,his name is Will Falconer 512-288-5400.Try holistic you might like it.
 

JamieB

Boxer Pal
Colitis

Dennis and Mary:
I work at a veterinary office with 5 different vets, and we have been through a multitude of things with Carli, my 10 month old rescue that has had persistent diarrhea, with fresh blood dripping from her bottom at times, but always mushy stool with blood in it. We first started antibiotics along with Metronidazole (flagyl) which would temporarily help, but never provided long-term relief. We finally did endoscopic biopsies of her intestine, which showed severe ulcers in her colon. The biopsies came back inconclusive other than that. Through my vets, I have learned that the best way to treat these guys is through trial and error. First, its important to pick a diet that is hypoallergenic to rule out any allergies. That's what we did. However, you mentioned a high protein diet that is allergy free. This is somewhat correct, to my knowledge. However, it seems contradictory. From what I know, the key to finding a food allergy is toying with the protein source: beef, chicken, venison, or no protein. Carli is on IVD (innovative veterinary diets) venison and potato, dried and canned. It's important, though, that when you try a diet with a different protein source, such as this venison diet, that you do not give your pet anything else to eat besides that diet. NO TREATS! NO tablefood! This is to make sure we isolate the diet to that one protein. If the dogs get anything else besides the food, there is no way of distinguishing what is causing the upset. We did try Science Diet I/D, but it did not help. Carli has only had relief from the venison and potato. There is another hypoallergenic diet called Science Diet Z/D in which the protein molecule is modified so the body does not recognize it, but this diet is known to maybe cause diarrhea, so we didn't try this. Carli also gets added fiber every day - 2 teaspoons of Metamucil in the morning and night on her food. We have also treated her with sulfasalazine. My biggest mistake was taking her off the Venison food when she got better. We did this to see if she really had a food allergy, or if she just had some ulcerative colitis that she had grown out of. She was on Eukanuba Adult, and was fine and was actually gaining weight for about a month, then the colitis returned. So now we are on the sulfasalazine, Metamucil, and venison and potato diet. We intermittenly use Metronidazole to help calm things down inside, so that she may be able to heal. My next plan of attack is to try yogurt and acupuncture. There is an veterinarian that does acupuncture and I have seen awesome results in neurological cases as well as allergy and incontinence cases. So, that is our next step. Please let me know if I can tell you anything else. Oh - on the steroids. Those are always an alternative, and my vet has thought about using Prednisone with Carli. However, because of her age, steroids will be the very last ditch effort to control this. They can interfere with some growing. So - we are going to ride it out from here. Let me know if I can be of any more help. Oh - and for Brutus and Amaya's mom, from what I have heard, the I/D and Sensitive stomach are almost identical.

Jamie
PS - Let me know periodically how these guys are doing. I will pass the suggestions on to my vets! It has been a learning experience for all of us.!
 

Sasha's Mom

Boxer Booster
Sulfasalazine - long term use

So now we are on the sulfasalazine, Metamucil, and venison and potato diet.

Jamie, thanks so much for the info. Do you give Carli the sulfasalzine daily or only when her symptoms return? If daily, are there any long-term side effects from taking this medication? We have had Sasha on a strict hypoallergenic diet (Waltham's selected protein (catfish and rice)) for the past month and a half, along with Sulfasalzine three times daily. Since her symptoms have been clearing up, we've been weaning her off the medication over the past few weeks and, as of this past Friday she has been off of it completely. We're sticking with the diet and will also start adding the metamucil and yogurt to her food (trying to cover all the bases and crossing our fingers that her symptoms do not reoccur). I'm all for placing her back on the meds if necessary, but would welcome any feedback regarding its long term use.

Thanks!

Susan
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JamieB

Boxer Pal
Long-term use of sulfasalazine

Well, I had also stopped the sulfasalazine, especially when she had normal stools with no blood. We also slowly switched her to Eukanuba adult, just to see if this was a food allergy. This was a very slow transition, over about a month and a half, and my vets have told me that if this is truly a food allergy in her case, the symptoms would have come back within about 6-7 days. But, for a month she did great on Eukanuba adult. She gained almost 5 pounds, and had normal stools. Then, all of the sudden, the bloody mushy stool came back. So, now we are back to square one. I kick myself for changing the food, but, how else were we to know if this was a food allergy. We are now thinking this is just a chronic colitis. I have put her back on the Sulfasalzine, and venison and potato diet (this is a dry dog food) since this is what seemed to get it under control in the first place. My vet has told me that Carli may always have to be on the Sulfasalazine. As far as long-term effects, I have not been told of any. However, I will double check for you. Another vet at my office went to continuing education, and we had a brief conversation yesterday about treatment with Tetracycline. The speaker at this conference has done studies on our pet's illness, and has pegged it as "Antibiotic Responsive Colitis" since most of these guys do respond to antibiotics. I will find out the rest of the information. However, it is getting really frustrating, because I don't know if there will ever be a time when she does not have to be on medication, a special food, or fiber. But, I want her to be healthy and happy. So, I will find out more info about these two drugs and I will get back to you!

Thanks!
Jamie
 

Sasha's Mom

Boxer Booster
Thanks, Jamie, I appreciate your input. It is frustrating, but I guess we should feel fortunate that our pups have responded favorably to the sulfasalzine. When our vet first prescribed it, she cautioned that we should watch for signs of excessive discharge/redness near the eyes and if she exhibited these symptoms we should discontinue the medication. Thankfully, Sasha tolerated the medication well, and actually took her pills rather easily (think she started thinking they were like treats since she no longer gets anything other than her prescribed food - she even sits up pretty for them). :)

As for long-term use, this morning I ran a search for this drug on http://www.rxlist.com and found the following notation under warnings:

"Ulcerative Colitis: Patients with ulcerative colitis should be made aware that ulcerative colitis rarely remits completely, and that the risk of relapse can be substantially reduced by continued administration of AZULFIDINE EN-tabs at a maintenance dosage."

Keep in mind this is referring to humans with ulcerative colitis, not necessarily canines with symptoms of colitis or ulcerative colitis. It made me feel a bit better though. The good news (I'm afraid to actually commit this to writing) is that so far, so good - her stools are still firm and blood free (and no meds since Friday). She loves her "special" food and really gobbles it up (whereas prior to this she was kind of a picky eater). Think she's even put on a few pounds.

Please keep me posted on Carli's progress and let me know if you find anything further on the meds. I will do the same.

BTW, off topic, but I notice you are from Missouri. My in-laws have a small farm in Fayette. We love it there - it's really a beautiful part of the country and the people are very friendly too. :)

Susan
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JamieB

Boxer Pal
Thanks for the information! Hopefully, Carli's symptoms will improve soon. We can also be thankful that our girls got such good homes. Many owners (from my experience at an animal hospital) would have been at their wits end, and may not have done nearly as much for their pets. Thanks again for the info.

BTW, I am around Kansas City, Missouri, in a suburb. We like it here, although I could do without the cold weather! I LOVE Florida. I have only been to Orlando, which is a little touristy, but the weather has always been great. And it is always beautiful. I have been in December, July, August, and November, and it has never let me down.

I will have to send you some pics of Carli!

Jamie
 
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