I need your help. We rescued our little girl boxer Princess Lea who is between the ages of 8-10 almost five months ago. She was diaginosed with breast cancer that we found out it had spread to a mass pushing on her heart. They gave her a month to live and that was three and a half months ago. She has put on weight, her coat is shiny and she is a happy and oh so loving dog. Since we have had her from day one she had chronic bladder infections. Her bladder would just leak out during the day. We cleared it up twice and now she still has the same issue of a leaking bladder. Her vet saw her yesterday and she is clear of infection. Our vet wanted to treat her for incontinence. She gave Princess Lea a prescription for PPA, 50mg one per night. She is also on Soloxine 0.3mg, 2 times a day. Well we gave her the first pill last night and we thought she was going to die. Thirty minutes after we gave her the pill she woke up at 10pm and starting panting very fast, her heart was racing, her eyes we bugged out and she was restless. For the next four hours she acted like she was running full speed down around the block, non-stop. She never acted like this even after we have taken her for a walk. We are very scared and want to know from our fellow boxer owners if they have every seen this, or if this is normal for this drug. Our vet said it's ok, but we don't want our P.L. stressing her little body out, especially at night when she should be resting. Since she has cancer and we are not sure how much time she may have, we want her to have dignity in regards to keeping herself clean of urine, but we also do not want to stress out her immune system.......any feedback or recommendations for other med's that have worked for incontinence?? Thanks!!